AMACR anticorps
Aperçu rapide pour AMACR anticorps (ABIN6296086)
Antigène
Voir toutes AMACR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human AMACR / p504S Antibody (Prostate Cancer Marker) [Sodium Azide Free]
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Specificité
- Cytoplasmic
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Purification
- A recombinant human protein was used as the immunogen for the AMACR antibody.
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Immunogène
- A recombinant human protein was used as the immunogen for the AMACR antibody.
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Indications d'application
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Immunohistology (FFPE): 1-2 μg/mL for 30 minutes at RT
IF: 1-2 μg/mL -
Restrictions
- For Research Use only
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Buffer
- In sterile PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Autre désignation
- Alpha-methylacyl-CoA racemase
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Sujet
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Target Description: AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
Gene Symbol: AMACR
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ID gène
- 23600
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UniProt
- Q9UHK6
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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